
2-(1,3-benzodioxol-5-yl)-N-methoxy-N-methyl acetamide
November 16, 2022
Ensitrelvir(S-217622) CAS:2647530-73-0
December 3, 20226-Chloro-2-methyl-2H-indazol-5-amine
6-Chloro-2-methyl-2H-indazol-5-amine is used as Ensitrelvir (S-217622) Intermediates. Ensitrelvir (S-217622) is an oral antiviral drug, which acts as an orally active 3C-like protease inhibitor for the treatment of COVID-19 infection. It has demonstrated antiviral effectiveness against Delta variant and the recently emerged Omicron variant. API CDMO can provide CDMO services for COVID-19 drugs with sufficient capacity, only for research use.
Product | 6-Chloro-2-methyl-2H-indazol-5-amine | ||
CAS No. | 1893125-36-4 | ||
Synonyms | Ensitrelvir intermediates;
2H-Indazol-5-amine, 6-chloro-2-methyl-. |
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SMILES | NC1=CC2=CN(C)N=C2C=C1Cl | ||
InChI | 1S/C8H8ClN3/c1-12-4-5-2-7(10)6(9)3-8(5)11-12/h2-4H,10H2,1H3 | ||
MF. | C8H8ClN3 | MW. | 181.62 |
Appearance | White to off-white powder | Purity | >95% |
Application | For research use only | Storage | Store at -20°C. |
COA & NMR | Download | MSDS | Download |
Other Ensitrelvir (S-217622) Intermediates:
6-(Ethylthio)-1-(2,4,5-trifluorobenzyl)-1,3,5-triazine-2,4(1H,3H)-dione
CAS: 2771355-74-7
3-(chloromethyl)-1-methyl-1H-1,2,4-triazole hydrochloride
CAS: 135206-76-7
6-(Ethylthio)-3-[(1-methyl-1H-1,2,4-triazol-3-yl)methyl]-1-[(2,4,5- trifluorophenyl)methyl]-1 ,3,5-triazine-2,4(1H,3H)-dione
CAS: 2771355-73-6
Reference
[1] “Japan’s Shionogi seeks approval for COVID-19 pill”. Reuters. 25 February 2022.
[2] World Health Organization (2022). “International nonproprietary names for pharmaceutical substances (INN): recommended INN: list 88”. WHO Drug Information. 36 (3): 89. hdl:10665/363551
[3] “Shionogi presents positive Ph II/III results for COVID-19 antiviral S-217622”. thepharmaletter.com. 31 January 2022.
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