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6-Fluoroindole
6-Fluoroindole is a halogen substituted indole. Experimental ionization potential of 6-fluoroindole has been evaluated. Preparation of 6-fluoroindole via nitration of indoline has been reported. Welcome customized 6-Fluoroindole powder from APICDMO!
| Product | 6-Fluoroindole | ||
| CAS No. | 399-51-9 | ||
| Synonyms | 6-FL;uoroindoL;
NSC 520436; 6-FLUOROINDOLE; 6-Fluro-1H-indole; 6-FLUORO-1H-INDOLE. |
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| SMILES | Fc1ccc2cc[nH]c2c1 | ||
| InChI | 1S/C8H6FN/c9-7-2-1-6-3-4-10-8(6)5-7/h1-5,10H | ||
| InChI key | YYFFEPUCAKVRJX-UHFFFAOYSA-N | ||
| Availability | In Stock | ||
| MF. | C8H6FN | MW. | 135.14 |
| Melting Point | 72-76°C | Boiling Point | 230℃ |
| Appearance | Beige-brown crystalline powder | Purity | 97% |
| Application |
For research use only |
Storage | RT |
| COA & NMR | Download | MSDS | Download |
6-Fluoroindole Application
6-Fluoroindole may be used as reactant in the preparation of:
❶ Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential Anticancer immunomodulators
❷ Antibacterial agents
❸ Antifungal agents
❹ Sodium-Dependent Glucose Co-transporter 2 (SGLT2) Inhibitors for the management of hyperglycemia in diabetes
❺ Potent selective serotonin reuptake inhibitors
❻ Inhibitors of HIV-1 attachment
Reference
[1] Full and Partial Agonism of a Designed Enzyme Switch. S Jimmy Budiardjo et al. ACS synthetic biology, 5(12), 1475-1484 (2016-07-09)
[2] 3-(2-(3-Pyridinyl)thiazolidin-4-oyl)indoles, a novel series of platelet activating factor antagonists.G S Sheppard et al.Journal of medicinal chemistry, 37(13), 2011-2032 (1994-06-24)
[3] Synthesis of 5-and 6-Halogenoindoles from Indoline. Ikan R, et al.Israel J. Chem., 2(2), 37-42 (1964),Journal of Medicinal Chemistry, 36, 2242-2242 (1993)
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