Organic chemical reagents differ from other commodities in that technologies such as synthesis,
separation, and detection will all play a role in determining whether or not the product quality is satisfactory.
Anaiji Chemical has developed its own production technology core through years of experience and exploration.
Technology of synthesis
It is primarily used in the synthesis of chiral compounds or chiral amino acids.
Mainly used for the synthesis of high-throughput screening compounds
It is primarily used in the synthesis of peptides.
Mostly used in polar organic molecule reactions.
It is primarily used in the synthesis of products that avoid high-toxicity reactions, complicated operations, and serious environmental pollution.
Reduce or eliminate the use and production of reactions or products derived from raw materials, catalysts, solvents and reagents, products, by-products, and so on that are hazardous to human health, community safety, and the environment.
Enzyme engineering, microbial fermentation engineering, and genetic engineering in organic synthesis are the most common applications.
For example
Anti-inflammatory and analgesic (S)-naproxen (22204-53-1) synthesis—— Annual sales of anti-inflammatory and analgesic (S)-naproxen reached $1 billion in the 1980s. Many scientists have successfully synthesized (S)-naproxen using various asymmetric methods. R-BINAP-Ru is used as the catalytic system in one of the asymmetric synthesis methods to achieve high stereoselectivity (e.g., 98%) and catalytic activity. The specific synthetic route is depicted on the right:
Typically used in reactions to separate liquid mixtures or remove high boiling point solvents.
Solvents are immiscible and are used for separation or purification of difficult-to-rectify substances. Solutes differ greatly in two solvents and do not react with solvents.
It is frequently used for the separation of impurities in large quantities of products that require significantly different solubility in a specific solvent.
Mostly used in polar organic molecule reactions.
Food, medicine, biology, water treatment, and other fields can all benefit from it.
A separation and purification method commonly used by organic chemists, but unsuitable for the separation of a wide range of substances.
It is primarily used to separate products or chiral compounds that are difficult to separate using conventional methods such as GC, HPLC, HPCE, SFC, and others.
Separation of solids and liquids
Separates solids and liquids (especially those with large amounts, which are slow to filter and easy to block the funnel)
For example
SFC separation technology has emerged as an important separation and analysis technology in recent years. It has the benefits of high separation efficiency, short separation time, good product quality, and easy detector matching. With the advancement of instrument and chromatographic column technology, it has become widely used in many fields, including the separation of chiral compounds and the separation and purification of natural products: for example, SFC technology can successfully separate evodiamine and evodiamine, and it can also be obtained from Artemisia annua extract. Artemisinin purification.
Technology for Detection
It is primarily used to identify the structural properties of organic compounds. The advancement of multi-dimensional NMR and NMR imaging technology in recent years has enabled NMR to be successfully applied in the fields of biology and medicine.
It is used to detect qualitative and quantitatively high boiling point and thermally unstable chemical substances, particularly drug molecules, as well as substances containing ultraviolet absorption and chiral compounds.
It is used for qualitative and quantitative detection of chiral compounds and other organic or inorganic samples with low boiling points and good thermal stability.
Mass spectrometry is one of the most powerful tools for determining pure substances, including relative molecular weight, chemical formula, and structural identification. Among these, a high-resolution mass spectrometer can provide the compound's composition formula.
It is an analysis method that employs liquid phase and mass spectrometry in tandem to aid in the analysis and identification of compound structures using NMR technology. It is currently widely used in drug metabolism and pharmacokinetics research, with a wide range of analysis.
It is an analysis method that employs gas phase and mass spectrometry in tandem to aid NMR technology in analyzing and identifying the structure of compounds. It is primarily used in drug metabolism and pharmacokinetic research.
Can identify and quantify the elements found in organic and inorganic substances.
Widely used in the qualitative identification and structural analysis of organic compounds, particularly unsaturated organic compounds and organic compounds with conjugated systems.
NMR will be used first for structure identification in our quality inspection process, followed by GC and HPLC for purity determination. When necessary, a combination of detection methods is used to ensure product quality.